I’m female with the normal blood type O+ He was K+. A few months later I became pregnant again, but fetal heartbeat was lost at 9 weeks. One antigen showed up in a our third pregnancy and now there are three with this fourth pregnancy. Kell is definitely one of the most aggressive but with trained maternal fetal medicine specialist Kell positive babies have a fighting chance. This means we can use the Punnett square again and see the genotypes of the offspring of a brown-eyed person (BB or Bb) and a blue-eyed person (bb). It is fairly certain Mary’s son cannot be Henry’s (the dates the king was near here don’t match up). The Kell factor refers to an antigen that’s attached to the membrane of red blood cells. 90% of the population is Kell negative. If your fetus is Kell+ your body will not attack it because it is the same as your blood type. Because I don’t really see the concern as you are R h positve. Your first child must have been Kell Positive and you were exposed to her blood in pregnancy or labor. The test result only means that you did not have COVID-19 at the time of testing. I am not a medical doctor, but I will give you all the information I have. Can anyone please shed some light on whether I have antigens or antibodies. Le rhésusest une particularité génétique : on est toujours du même rhésus qu'il soit positif ou négatif. But how did Henry get that Kell positive gene? Thanks for the answer. I’m the first child of my parents (Kk, my father is KK, my mother is kk). It could carry through the father’s line, since the eldest child could survive having the Kell antigen (Kk) but it is most often via the mother. I have a 3 year old daughter and my blood test was negative for anti kell antibodies when I had her. I say that it’s more look like a woman with a blood type of “-” marrying a man with blood type “+”. and where that came from? It could avoid heartbreak in the future. What does it mean if I'm rhesus negative? KK people are VERY rare. Has he been phenotyped. Thanks so much for your help.The whole thing is very confusing. People who have that blood have golden blood to me. I wish I could tell you with 100% certianty that this baby will be unaffected, but I can’t. I hope this pregnancy and any future pregnancies go smoothly and without complications! How have I got these antibodies? If the girl is either Kell positive or negative, it shouldn’t be a problem for her. Or maybe none of them will be. I am sorry that this got trapped in my comment filter and I just saw it. He is 100% the father as well. If the baby does have the cellano gene, then your titers will start to show it and the doctors can respond as needed. A very simplified version of how a dominate gene (especially one that is harmful under certain conditions) can wind up being in only a small minority of a population. Menu. The ABO gene found on chromosome 9 determines the ABO blood group system. Does that help clear things up at all? If he is indeed homozygous then I have no idea whatsoever why your other pregnancies didn’t have severe complications. Try not to worry. My husbands blood work came back negative for the kell antigen. Probably Anti-K based on what you described. Should my children be told or even be concerned that they are Kell positive f. A couple of years ago I had a 13 week ultrasound scan for my pregnancy which showed severe fetal hydrops/cystic hygroma, incompatible with life and therefore the pregnancy had to be terminated. Cheers. So how do you know he is Kell antigen positive. Is that possible? I didn’t have them in my first and haven’t had a transfusion. I just have a biology degree and study doctors. Any babies before or after that Kell positive pregnancy that did NOT inherent the Kell antigen were NOT affected. That episode stressed me out a lot I had to ask my parents about it without telling them Im pregnant… but im glad it was just a mistake. We have patients getting tranfused liters of K+ blood who don’t ever develop antibodies, much less women from their babies. I worry, a little, for my half-brother and my sister’s son, that they will have trouble if they want 2 kids, or if they have a partner who has had a prior Kell+ transfusion to react to. Again, I am sorry for your many losses and I hope you have reproductive success in the future. 2. Thankful to The Lord! I was thinking maybe my grandson’s mother should get tested just in case. Your blood type us A and you are Rh. However, it is the third most common blood type which is present in about 1 out of 12 individuals. 2. He had some jaundice, and was in an incubator for awhile, but it wasn’t too serious. I contracted the Kell antibody because of a blood transfusion I had after my 1st pregnancy which was a c-sec. Not sure why this came to mind but it dis, perhaps I’m trying to occupy my time while we wait for the blood work. **Please note, I am not a medical professional, so please forgive any errant use of medical terms in the following**. I hope the information I sent via Facebook chat will help. This is my first pregnancy after a year of trying (about 7 weeks now) and I am very worried…Do you have any advice for me please? so far me and my husband who is the father to both of my children, are barely finding out information on this. This test is frequently performed on newborn babies. This exact scenario actually happened to me. Just make sure s/he remembers/knows your last pregnancy had this issue. A little bit about the Kell positive blood type, on A little bit about the Kell positive blood type, Click to email this to a friend (Opens in new window), Click to share on Facebook (Opens in new window), Click to share on LinkedIn (Opens in new window), Click to share on Reddit (Opens in new window), Click to share on Twitter (Opens in new window), Click to share on Tumblr (Opens in new window), Click to share on Pinterest (Opens in new window), Click to share on Pocket (Opens in new window), Click to share on Telegram (Opens in new window), Click to share on WhatsApp (Opens in new window), Click to share on Skype (Opens in new window), http://www.sciencealert.com/artificial-blood-could-be-used-in-trial-transfusions-by-2016. since then ive had 2 miscarriages til now. As far as we know I am the only one in my family that has this. What blood tests do I need during pregnancy? If you test positive, know what protective steps to take to prevent others from getting sick. Kell is not a blood type it is antigen found on the red blood cell. (Yes, even five in a row. Either way, your babies are safe from issues due to Kell. Just wanted to add my blood type is A+ , my mum told me I had jaundice and mild anemia when I was born. If I am Kell +, & My husband is Kell -, babies + or – is currently unknown . People with Mcleod syndrome can have major issues, or actually be mostly OK (the person it was discovered in went to Harvard), but the gene for it is really close to the gene for chronic granulomatous disease which is bad business. Any advice? Moreover, random chance can make a dominate gene go bye-bye even when the dominate gene doesn’t cause the death of many offspring who inherit it. If it is a first pregnancy, then the mother’s body will not attack the fetus even if it is Kell positive. I would hate for his future wife to go through the scare I had, or since Dad is Neg & my pregnancy was “normal” is my son kell free? We also don’t know if the baby is definitely negative if antibodies have shown up in the first place…. It can be used in many aspects, referring to: what, how much or how high one gets. We won’t know if he is heterozygous or homozygous, but hopefully he will be negative and that will be the end of it. Well, my first instinct is to wonder if you got a false positive or if your husband got a false negative. If they are Kell negative, you’ll know the test for your husband was off a bit and that he is Kk, not KK. I have no IDEA how the body’s immune system can by ‘twisted’ to decry you as a person or mother; it would take extreme asshattery on the part of your husband’s family. if the mother has anti kell anti bodies and the father has a kell positive (heterozygous) Kk. Baby 3 I had to have a c sec and transfusion. Please see Bombay phenotype for a similar situation, these people genetically maybe should be A, or B, but are missing the “foundation” so they don’t express the antigens. My blood was tested and I was negative for at least one of the antigens. However, if you have a Kell+ son and his future partner is Kell- then they need to give her a doctor a heads up when/if she gets pregnant. In other words, please do not sugarcoat or downplay the possibility for fear that this could set some sort of disruptive chain of events in a family’s life somewhere. (obsolete) The caul. we cannot trace the family tree and were wondering if there was a spot in the world it showed up with more incidence, helping us to know our roots? Thank you very much, I had quite the scare and was so mad about the whole thing . I sincerely hope this reply finds you well and delivered of a healthy second child!!!!! I sincerely appreciate your consideration. This is in addition to the ABO blood groups that most people know about. I have K antibodies, my husband is apparently negative with kk. 2) All four kids are K positive. Okay, the GOOD news is that as a K+ woman your pregnancies will never be effected. I wish I could be of more help, but I am not a medical doctor … I just study the culture of medicine. Thank you for the advice Kyra! Random chance works like that. At 33 weeks, she is with the range of viability so even if your body starts attacking they can induce your labor and ‘rescue’ her from a hostile uterine environment. Are they overrated or is it a big deal? What this means is you can place your iPhone on a wireless charging pad and the iPhone would charge wirelessly without having to connect a charger. RBcs are packed RBCs they do not contain serum,so with that said RBcs contain antigen. If #9 is a boy, every pregnancy after his wife’s first will need to be watched by an OB/Gyn who knows she might be carrying a Kell+ fetus — unless his wife is K+ too, which is rare. so far the doctors are thinking that i got this anti-body from the transfusions since we r still waiting on my husbands blood test from last week. Une personne est rhésus négatif si ses globules rouges ne portent pas à leur surface de mol… Today my husbands blood work came back as negative just as your husbands did. When we tell people and ourselves to stay positive or look on the bright side of things, what do you look for, think of, say, or do if you are being positive? Or if I get pregnant again will it come back? There are apparently quite a few antigenic things that can be running around on the surface of your red blood cells. However, a wise doctor would panic and NOT push the issue … just in case. I have the same situation as you, during the 6-th pregnancy it appeared I have Kell antigens. The drs will need to do invitro transfusions into the placentas ; however baby A’s is close to her front belly but baby B’s placenta is planted towards her back and that makes it very difficult to perform the transfusions. And yet, 38 years later, here I am. . My hope is that there are other explanations and whatever the answer, that I can either face the issue or bury the doubt. There is unlikely to be any insurmountable obstacles preventing your from having children … it may just take longer and be harder. I’m 34 years old. Does this mean my SS2 has a Kell positive blood type and can I get him tested to see? Never mind about the question, I asked it wrong can a Kk pass only positive onto a child or can they still pass the negative too? Yes. Sorry, your blog cannot share posts by email. They did a titer all they told me was that it is an 8 ?…. We have been trying for years to have a 2nd baby, I have had several misscarriages so those were probably Kell positive babies. Your case is certainly different from the norm! Antibodies can become unexpressive and the antibody screen will be negative and if your history is not known blood will not be antigen typed. This means there is a 91% chance your husband is kell negative too! Hi, Quick question. In the ABO blood system, type O positive blood is common, about 36% of the population. I will not be having any more children, but am concerned that it may be an issue for them when they have children. Thanks. Thanks so much for this info, it explains so much and I understand it so much better. or they overrated!! Kyra and Rebecca Ware, Even when you are mentally prepared, they can still break your heart. He is the father of my two boys, and this third pregnancy where these antibodies have shown up for the first time. There are apparently quite a few antigenic things that can be running around on the surface of your red blood cells. First, I am sorry for the loss your brother and SIL went through. My kids were all blood typed as O+. You cannot have both. Debbie from NY. Moreover, they only consider it odd enough to start testing things if you lose 3 babies in a row. Exposure to Kell causes one to develop Anti-Kell, but Kell itself is a genetic trait. If you get a non-Kell sperm then (if all else is normal) you will have a healthy pregnancy and a hearty little baby at the end of it without any big medical interventions. Prior to the test I was told that I would have the antigens (or antibodies) because my wife was reacting to them from blood from the prior babies / umbilical cord getting into her system from the prior C Sections and that the effectively half of the foreign blood came from me as the kids were a mix of my and my wife’s blood. However, your should be safe on the Kell front. My wife is pregnant with our fourth child and has had three prior C Sections. Maybe it is on your post it is pretty late. Antibodies are found in serum/plasma. I can’t have blood transfusions unless they have an exact match as me. Hi Kyra thanks for replying. My OB says my blood is normal. I have never had a blood transfusion and was A+ all my life until after baby #1. You should now take the advice from a MFM vs an OB. Hoping that it will help young girls/women of childbearing age. I have Orthostatic Hypotension and after my 1st baby girl I ruptured a vein causing me to lose blood when I was already anemic and had a lowish blood count. … Thank you so much. And that’s awesome you have 3 precious babies! No worries! I suppose the confusion is because Kell is an antigen, so Anti-Kell is an anti-antigen? My sincere hopes for your future reproductive success. Une personne estrhésus positif (+)si ses globules rouges portent, à leur surface, une certaine molécule, appelée molécule rhésus. Because there is a more than 90% chance that one of their parents was Kell negative, and thus had only k genes to bring to the party. Hopefully I am going for an ultersound soon to Check blood flow in brain.as I am 17 weeks now. And even if he DID have the Kell gene, there is lots they could do for his future reproductive partner, and many people with K+ men get lucky and get 3 Kell negative babies in a row. My wife and I have a son (Kell blood type unknown) and we have just found out my wife is pregnant again. So if she becomes pregnant with a Kell-positive baby, her anti-Kell antibodies might cross the placenta and destroy the baby’s red blood cells. They did blood work for my husband he turn out to be k negative. However, your sibling’s birth is unusual because there should have been enough alloimmunization to effect the pregnancy. Your first pregnancy will not be affected by kell antigens (but could still be one of the 1/3 lost pregnancies; there are lots of things that can go wrong with a normal pregnancy). Since there is only a 50/50 of a first born getting the K gene, maybe only 2 out of the 16 hypothetical grandchildren will be Kell positive. Is Kell only spread by the men? However, not all of the ethnic groups share the same proportions of blood types. Bc my antibodies no longer titered my OB did NOT want to do an amnio to determine if my baby was K+. With McLeod that foundation is malformed, thus the “houses” are missing or weak. (Sadly, two losses in a row are common; docs don’t usually ‘worry’ until the third.) So no, it is not rare. The Kell antigen system (or the Kell-Cellano system) was named after the family of the antibody producer Mrs. Kellacher. I am currently 18 weeks pregnant. Seriously, and no sugarcoating, there is no real reason to think the kids aren’t biologically your progeny. (Well, it used to be like that before modern medical treatments that will keep a Kell positive fetus alive inside a Kell negative mother. I have just found out that I had K antibodies in my blood tests in my second pregnancy. Would the baby’s blood attack moms blood? What are some viable reasons these antigens could be in her system? So as I understand all my other babies were kell negative and if this baby is kell postive my body will give this baby a chance ? If your body had a really strong response vis-a-vis antigens, then only your body can handle your blood, plasma, ect … Also, a really strong anti-Kell response by your body might indicate a significant risk for your next fetus, in spite of all the medical technology, if it is Kell positive too. It is an antigen on the red blood cell. I had two miscarriages a year ago. And I am now pregnant waiting in test results. I have been searching all over the net to answer my question but only find general references to “testing” but no explanation of how one goes about testing to see if kell or other similar things are the cause of recurrent pregnancy losses between two partners. Thank you for clearing up all of these things and I appreciate the guidance about having my kids tested. Stress can also hurt you and the baby. Okay, I’m trying to remember science in middle school, having a tough time. I would encourage you if you are ever hospitalized to be sure that you tell your nurses and doctors that you have an antibody. Egg. But not a freak. Does anyone stop to ask what “testing positive for coronavirus” means? We are waiting for the results of my husbands bloodwork, I have Kell and Kidd antibodies. The doctor told me that my anemia is not the same as the baby’s anemia, as you and your baby do not share the same blood. If your husband is Kk then the babies could have the Kell antigen. I was born 3 weeks early, with jaundice much more severe than my sister or brother had. The antibodies are usually made after a blood transfusion.. We are waiting for my son’s results right now. My hubby tested positive for kell antigen and is homogenous for kell so all our kids are kell positive , can you please explain how he is homogenous for kell antigen , my pregnancy is now 34 weeks and my tillers have remained stable at 1:28 but today have doubled , baby shows no signs of anaemia via mca scan and no signs of hydrous but they want to deliver in 2 weeks , what does the rise in antibodies mean? If you test positive for COVID-19—or suspect that you have it—it is important that you follow recommendations from the Centers for Disease Control and Prevention (CDC) to stop the spread. You’re actually Kk, which means you have a Kell+ gene and one without it. My third child, another daughter was born with no issues whatsoever. Did her Ob/Gyn not test for Kell antibodies in her blood after the third miscarriage? Their children have the potential genotypes of: We know two things from these squares and the fact Kell positive blood is rare. Un groupe sanguin comprend une lettre A, B ou O et un signe + ou –. However, if your husband doesn’t have the Kell gene to give your baby, then your body should have no reason to attack her. When antibodies are found on the mother’s red blood cells, the mother is referred to as being “Kell positive.” What Does It Mean to Be Kell Positive or Kell Negative? And the most common for Europeans and Africans was the K-k+. The BAD news is that if either of your sons have your blood type then their partners might (and it is a big if considering genetics) have issues IF the partner is a normal K- and IF the second fetus is K+. But it is actually MUCH MUCH MORE COMMON to NOT develop antibodies. thanks. I am currently in the same situation and am totally baffled! I think if your antibodies are that high, then your body has been sensitized. The presence of Kell antibodies can be detected by maternal blood testing. They way they check the baby is through ultrasound and Doppler. I wonder if my blood type is actually a connector, although according to the heredity patterns, could the Kk have survived through a father line? In reference to any weed related matter, often used as a code word. but my husband is still worried about the babys health and how my health will fare. And what about you have you been antigen typed for Kell. Usually the blood is taken from the baby’s cord while it is attached to the placenta following delivery. I feel like even if the baby is negative and so is my husband that there could still be problems with myself? I hope he is not Kell positive, but I have to tell you that yes he could be. This is assuming the blood tests are all correct. I wonder if there is anyway that we can change this? I have three children. I have hereditary O RH + Kell blood group past to me from my father which I know is very rare (I’m on the rare blood type register). Will this be a health problem for me later in life. How can that be? Any of your children could be Kk because as a Kell positive mom, your body wouldn’t harm them with or without the Kell gene. If you need more support with Kell… Look up the “ISO moms” group on Facebook. First, let me congratulate you on your twins! My husbands waiting to get results to find out if he is kell pos. If you love him, marry him. After my first born I had a transfusion that obviously contained the Kell antibodies. I love my wife and my kids, regardless of their origin. Well, here I am a year later and I had blood work done the other day and my blood showed NO kell. Either the Kell did not ‘turn on’ and make itself known, or your mom’s body doesn’t have a profound alloimmunizational response. For one thing, people who are homozygous (KK) for Kell are rare. I hope I explained why your last healthy baby could have been unknown Kell positive adequately? I wrote you earlier, but my blog didn’t post it. Also I think maybe some people are getting g mixed up on this sight. I became Kell antigen positive after receiving a blood transfusion while giving birth. If you are antigen typed and are Kell negative then you have the possibility of formin g antibodies if exposed to the Kell antigen. Her pregnancy with SS2 was just fine but she did have a C-sections and was "exposed" to this antigen or whatever it is. Yes, Rh and Kell antibodies are a concern because tend to be relatively immunogenic and cause more severe hemolytic disease of the newborn because they are expressed by a fetus so early and women lose babies. I hope that helps. Some people have it; some don’t. An RhD positive baby will only have rhesus disease if their RhD negative mother has been sensitised to RhD positive blood. Remember, YOU are here and you were obviously a Kell+ fetus at one point. Those antigens can doge a test more than people realize. so far the baby is looking fine and healthy. The baby could miscarry or die of hemolytic disease of the newborn if your wife unknowingly has the anti-Kell antigens and steps aren’t taken. Le système Rhésus est un système complexe qui comporte plusieurs antigènes dont le plus important pour la transfusion est l’antigène D. Sur les globules rouges des sujets dits Rhésus négatifs l’antigène D n’est pas présent alors qu’il l’est chez les sujets Rhésus positif. However, get more than one test to be sure. That means all the children except for the first, your daughter, and #9 will be almost axiomatically Kell negative. If the fetus is Kell- then there is no antigen there to cause your body to have alloimmunization. the placenta broke inside her thus getting blood from the baby who’s dad tested positive) it’s so complicated and I worry so much since the dr. said her case is the first they have seen in that hospital (they live in Calif. ) . Would you kindly give me you contacts, if possible, I’ll ask you some questions. The good news is that, as far as I can tell, your husband’s lack of a Kell positive gene means your body will not reject the fetus you are carrying. Dominate browns can easily be hiding secret blue genes (insert blue jean joke here) but the brown B is gone once the recessive have the field. Was that the end of the drama? Let’s say mom has brown eyes of BB and dad has blue. If there is no Kell positive fetus/embryo in your uterus then your body won’t be making the anti-Kell stuff to attack it with, so there shouldn’t be enough to show up. To have Kell positive blood means you have at least one of the Kell antigens on your red blood cells. It says K-k+ is the most common Kell group in Europeans. If you do get a Kell positive fetus then there ARE things the doctor can do to save the pregnancy. If you only have two or three children, you may never even have a Kell-effected pregnancy, because you might have the good luck that the babies never get your husband’s genes. It again, there is a possibility is Kell+ your body to have Kell Kidd! Where antigens are K, they only consider it odd enough to start things. With an antibody screen that screen will be a health problem for her can hardly it. Does not, sadly, two losses in a blood transfusion and was A+ all life. This means breast cell development almost certainly kill me doctor by 12 wks attached. I cried until his results came back from my first daughter would be the one who the! ( sadly, rule out any other disaster — but from the baby s. 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